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High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Posaconazole and Vincristine in Rat Plasma

Purpose. Developing a validated HPLC-DAD method for simultaneous determination of posaconazole (PSZ) and vincristine (VCR) in rat plasma. Methods. PSZ, VCR, and itraconazole (ITZ) were extracted from 200 μL plasma using diethyl ether in the presence of 0.1 M sodium hydroxide solution. The organic la...

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Detalles Bibliográficos
Autores principales: Khalil, Hadeel A., El-Yazbi, Ahmed F., Belal, Tarek S., Hamdy, Dalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807048/
https://www.ncbi.nlm.nih.gov/pubmed/27034675
http://dx.doi.org/10.1155/2015/743915

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