Cargando…

Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia

Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB-induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that lowering Pax7 expression may be beneficial in cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coletti, Dario, Aulino, Paola, Pigna, Eva, Barteri, Fabio, Moresi, Viviana, Annibali, Daniela, Adamo, Sergio, Berardi, Emanuele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807049/ https://www.ncbi.nlm.nih.gov/pubmed/27034684 http://dx.doi.org/10.1155/2016/6729268

Ejemplares similares

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer
por: Pigna, Eva, et al.
Publicado: (2016)

Substrains of Inbred Mice Differ in Their Physical Activity as a Behavior
por: Coletti, Dario, et al.
Publicado: (2013)

Skeletal Muscle: A Significant Novel Neurohypophyseal Hormone-Secreting Organ
por: Adamo, Sergio, et al.
Publicado: (2019)

Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse
por: Aulino, Paola, et al.
Publicado: (2010)

Increasing autophagy does not affect neurogenic muscle atrophy
por: Pigna, Eva, et al.
Publicado: (2018)

Of Faeces and Sweat. How Much a Mouse is Willing to Run: Having a Hard Time Measuring Spontaneous Physical Activity in Different Mouse Sub-Strains
por: Coletti, Dario, et al.
Publicado: (2017)

A Pound of Flesh: What Cachexia Is and What It Is Not
por: Berardi, Emanuele, et al.
Publicado: (2021)

Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice
por: Renzini, Alessandra, et al.
Publicado: (2022)

Displaced Myonuclei in Cancer Cachexia Suggest Altered Innervation
por: Daou, Nissrine, et al.
Publicado: (2020)

HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses
por: Pigna, Eva, et al.
Publicado: (2018)

Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis
por: Pigna, Eva, et al.
Publicado: (2019)

Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis
por: Costa, Alessandra, et al.
Publicado: (2014)

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment
por: Aulino, Paola, et al.
Publicado: (2015)

Denervation does not Induce Muscle Atrophy Through Oxidative Stress
por: Pigna, Eva, et al.
Publicado: (2017)

Modulation of Caspase Activity Regulates Skeletal Muscle Regeneration and Function in Response to Vasopressin and Tumor Necrosis Factor
por: Moresi, Viviana, et al.
Publicado: (2009)

The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio
por: Baccam, Alexandra, et al.
Publicado: (2019)

Histone Deacetylases as Modulators of the Crosstalk Between Skeletal Muscle and Other Organs
por: Renzini, Alessandra, et al.
Publicado: (2022)

The JAK/STAT Pathway in Skeletal Muscle Pathophysiology
por: Moresi, Viviana, et al.
Publicado: (2019)

Muscle acellular scaffold as a biomaterial: effects on C2C12 cell differentiation and interaction with the murine host environment
por: Perniconi, Barbara, et al.
Publicado: (2014)

Coordinated Actions of MicroRNAs with other Epigenetic Factors Regulate Skeletal Muscle Development and Adaptation
por: Bianchi, Marzia, et al.
Publicado: (2017)

Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?
por: Gonçalves, Renata de Castro, et al.
Publicado: (2021)

Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia
por: Di Felice, Valentina, et al.
Publicado: (2022)

Functional Nutrients to Ameliorate Neurogenic Muscle Atrophy
por: Moresi, Viviana, et al.
Publicado: (2022)

HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors
por: Renzini, Alessandra, et al.
Publicado: (2018)

Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance
por: Harvey, Alexandra, et al.
Publicado: (2019)

Heme metabolism genes Downregulated in COPD Cachexia
por: Wilson, Ava C., et al.
Publicado: (2020)

Molecular and cell-based therapies for muscle degenerations: a road under construction
por: Berardi, Emanuele, et al.
Publicado: (2014)

Culture conditions influence satellite cell activation and survival of single myofibers
por: Renzini, Alessandra, et al.
Publicado: (2018)

Sex Differences in Inflammation and Muscle Wasting in Aging and Disease
por: Della Peruta, Chiara, et al.
Publicado: (2023)

Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia
por: Chiappalupi, Sara, et al.
Publicado: (2020)

Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy
por: Renzini, Alessandra, et al.
Publicado: (2022)

PGC-1α in the myofibers regulates the balance between myogenic and adipogenic progenitors affecting muscle regeneration
por: Beltrà, Marc, et al.
Publicado: (2022)

Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression
por: Barone, Rosario, et al.
Publicado: (2016)

Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1
por: Yu, Jiyeon, et al.
Publicado: (2021)

Retina regeneration in the chick embryo is not induced by spontaneous Mitf downregulation but requires FGF/FGFR/MEK/Erk dependent upregulation of Pax6
por: Spence, Jason R., et al.
Publicado: (2007)

PKCθ signaling is required for myoblast fusion by regulating the expression of caveolin-3 and β1D integrin upstream focal adhesion kinase
por: Madaro, Luca, et al.
Publicado: (2011)

Pax7 is back
por: Brack, Andrew S
Publicado: (2014)

Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle
por: de Castro, Gabriela S., et al.
Publicado: (2019)

Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies
por: Sandonà, Martina, et al.
Publicado: (2023)

Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis
por: Kuang, Shihuan, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_nufif6ea89j6q7arfo79o9om6u