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Genomic Characterization and Comparison of Multi-Regional and Pooled Tumor Biopsy Specimens
A single tumor biopsy specimen is typically used in cancer genome studies. However, it may represent incompletely the underlying mutational and transcriptional profiles of tumor biology. Multi-regional biopsies have the advantage of increased sensitivity for genomic profiling, but they are not cost-...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807092/ https://www.ncbi.nlm.nih.gov/pubmed/27010638 http://dx.doi.org/10.1371/journal.pone.0152574 |