Cargando…

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease

In Parkinson’s disease (PD), alpha-synuclein (a-syn) can be detected in biological fluids including saliva. Although previous studies found reduced a-syn total (a-syn(total)) concentration in saliva of PD patients, no studies have previously examined salivary a-syn oligomers (a-syn(olig)) concentrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vivacqua, Giorgio, Latorre, Anna, Suppa, Antonio, Nardi, Michela, Pietracupa, Sara, Mancinelli, Romina, Fabbrini, Giovanni, Colosimo, Carlo, Gaudio, Eugenio, Berardelli, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807094/ https://www.ncbi.nlm.nih.gov/pubmed/27011009 http://dx.doi.org/10.1371/journal.pone.0151156

Ejemplares similares

Salivary α‐Synuclein RT‐QuIC Correlates with Disease Severity in de novo Parkinson's Disease
por: Vivacqua, Giorgio, et al.
Publicado: (2022)

Parkinsonian Patients and Poor Awareness of Dyskinesias
por: Pietracupa, Sara, et al.
Publicado: (2014)

Neuroimaging advances in Parkinson's disease with freezing of gait: A systematic review
por: Bharti, Komal, et al.
Publicado: (2019)

Microtubule Depolymerization Potentiates Alpha-Synuclein Oligomerization
por: Esteves, A. Raquel, et al.
Publicado: (2010)

Salivary caffeine in Parkinson’s disease
por: Leodori, Giorgio, et al.
Publicado: (2021)

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD
por: Esteves, A. R., et al.
Publicado: (2011)

Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein
por: Abdi, Ilham Y., et al.
Publicado: (2021)

Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson’s disease patients
por: Kang, Wenyan, et al.
Publicado: (2016)

Distal Upper Limb Tremor during Walking in Parkinson's Disease
por: Costanzo, Matteo, et al.
Publicado: (2023)

Antibodies against Alpha-Synuclein Reduce Oligomerization in Living Cells
por: Näsström, Thomas, et al.
Publicado: (2011)

In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis
por: Ouzounoglou, Eleftherios, et al.
Publicado: (2014)

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
por: Majbour, Nour K., et al.
Publicado: (2016)

Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
por: Lázaro, Diana F., et al.
Publicado: (2014)

Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein
por: Delenclos, Marion, et al.
Publicado: (2017)

Does the Somatosensory Temporal Discrimination Threshold Change over Time in Focal Dystonia?
por: Conte, Antonella, et al.
Publicado: (2017)

Neuropsychiatric disturbances in atypical parkinsonian disorders
por: Belvisi, Daniele, et al.
Publicado: (2018)

The Role of Alpha-Synuclein Oligomerization and Aggregation in Cellular and Animal Models of Parkinson’s Disease
por: Wan, Oi Wan, et al.
Publicado: (2012)

Dataset of total, oligomeric alpha-synuclein and hemoglobin levels in plasma in Parkinson׳s disease
por: Emelyanov, A., et al.
Publicado: (2016)

How epigallocatechin gallate binds and assembles oligomeric forms of human alpha-synuclein
por: Andersen, Camilla B., et al.
Publicado: (2021)

The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation
por: Lázaro, Diana F., et al.
Publicado: (2016)

Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice
por: Cai, Waijiao, et al.
Publicado: (2018)

The Emerging Role of Ferroptosis in Liver Cancers
por: Casini, Arianna, et al.
Publicado: (2022)

Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium
por: Casini, Arianna, et al.
Publicado: (2023)

Parkinsonism Is Associated with Altered SMA-Basal Ganglia Structural and Functional Connectivity in Frontotemporal Degeneration
por: Piervincenzi, Claudia, et al.
Publicado: (2023)

A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo
por: Delenclos, Marion, et al.
Publicado: (2016)

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants
por: Tosatto, Laura, et al.
Publicado: (2015)

Small Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein
por: Ghosh, Sumanta, et al.
Publicado: (2018)

Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
por: Doucet, Marika, et al.
Publicado: (2017)

Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies
por: Outeiro, Tiago Fleming, et al.
Publicado: (2008)

Combined measure of salivary alpha-synuclein species as diagnostic biomarker for Parkinson’s disease
por: Angius, Fabrizio, et al.
Publicado: (2023)

Frontotemporal dementia: a neurophysiological study
por: Di Stasio, Flavio, et al.
Publicado: (2018)

Inhibition of Calpain Prevents Manganese-Induced Cell Injury and Alpha-Synuclein Oligomerization in Organotypic Brain Slice Cultures
por: Xu, Bin, et al.
Publicado: (2015)

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
por: Majbour, Nour K., et al.
Publicado: (2017)

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis
por: Hughes, Craig D., et al.
Publicado: (2018)

Abnormal Temporal Coupling of Tactile Perception and Motor Action in Parkinson’s Disease
por: Conte, Antonella, et al.
Publicado: (2017)

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization
por: Calogero, Alessandra Maria, et al.
Publicado: (2023)

Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism
por: van Rooijen, Bart D., et al.
Publicado: (2010)

Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein
por: Roberts, Hazel L., et al.
Publicado: (2015)

Oligomerization by co-assembly of β-amyloid and α-synuclein
por: Kim, Jin Ryoun
Publicado: (2023)

Abnormal Resting-State Functional Connectivity in Progressive Supranuclear Palsy and Corticobasal Syndrome
por: Bharti, Komal, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_as0669o8qcf2a79op6dpo2d4hp