Cargando…

Structural Analysis of Free N-Glycans in α-Glucosidase Mutants of Saccharomyces cerevisiae: Lack of the Evidence for the Occurrence of Catabolic α-Glucosidase Acting on the N-Glycans

Saccharomyces cerevisiae produces two different α-glucosidases, Glucosidase 1 (Gls1) and Glucosidase 2 (Gls2), which are responsible for the removal of the glucose molecules from N-glycans (Glc(3)Man(9)GlcNAc(2)) of glycoproteins in the endoplasmic reticulum. Whether any additional α-glucosidases pl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hossain, Tanim Jabid, Harada, Yoichiro, Hirayama, Hiroto, Tomotake, Haruna, Seko, Akira, Suzuki, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807098/ https://www.ncbi.nlm.nih.gov/pubmed/27010459 http://dx.doi.org/10.1371/journal.pone.0151891

Ejemplares similares

N-glycan Remodeling Using Mannosidase Inhibitors to Increase High-mannose Glycans on Acid α-Glucosidase in Transgenic Rice Cell Cultures
por: Choi, Hong-Yeol, et al.
Publicado: (2018)

Synthesis of Isomaltooligosaccharides by Saccharomyces cerevisiae Cells Expressing Aspergillus niger α-Glucosidase
por: Casa-Villegas, Mary, et al.
Publicado: (2017)

Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo
por: Stigliano, Ivan D., et al.
Publicado: (2011)

Production of galactosylated complex-type N-glycans in glycoengineered Saccharomyces cerevisiae
por: Piirainen, Mari A., et al.
Publicado: (2021)

Endolysosomal N-glycan processing is critical to attain the most active form of the enzyme acid alpha-glucosidase
por: Selvan, Nithya, et al.
Publicado: (2021)

N (α)-arylsulfonyl histamines as selective β-glucosidase inhibitors
por: Salazar, M. O., et al.
Publicado: (2018)

Directed evolution of a fungal β-glucosidase in Saccharomyces cerevisiae
por: Larue, Kane, et al.
Publicado: (2016)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
por: Sansenya, Sompong, et al.
Publicado: (2020)

Unique Microbial Catabolic Pathway for the Human Core N-Glycan Constituent Fucosyl-α-1,6-N-Acetylglucosamine-Asparagine
por: Becerra, Jimmy E., et al.
Publicado: (2020)

Fishing of α-Glucosidase’s Ligands from Aloe vera by α-Glucosidase Functionalized Magnetic Nanoparticles
por: Yuan, Hao, et al.
Publicado: (2021)

Engineering Saccharomyces cerevisiae with the deletion of endogenous glucosidases for the production of flavonoid glucosides
por: Wang, Huimin, et al.
Publicado: (2016)

Effects of Hydroxyl Group on the Interaction of Carboxylated Flavonoid Derivatives with S. Cerevisiae α-Glucosidase
por: Lu, Huining, et al.
Publicado: (2020)

Co-Expression of NEU2 and GBA3 Causes a Drastic Reduction in Cytosolic Sialyl Free N-glycans in Human MKN45 Stomach Cancer Cells—Evidence for the Physical Interaction of NEU2 and GBA3
por: Wang, Li, et al.
Publicado: (2015)

Characterization of gene-activated human acid-β-glucosidase: Crystal structure, glycan composition, and internalization into macrophages
por: Brumshtein, Boris, et al.
Publicado: (2010)

Protocol for analyzing the biosynthesis and degradation of N-glycan precursors in mammalian cells
por: Harada, Yoichiro, et al.
Publicado: (2021)

Peptide Sequence Mapping around Bisecting GlcNAc-Bearing N-Glycans in Mouse Brain
por: Ohkawa, Yuki, et al.
Publicado: (2021)

Synthesis of N-Substituted Iminosugar C-Glycosides and Evaluation as Promising α-Glucosidase Inhibitors
por: Wang, Haibo, et al.
Publicado: (2022)

Synthesis of Novel N-Methylmorpholine-Substituted Benzimidazolium Salts as Potential α-Glucosidase Inhibitors
por: Khan, Imran Ahmad, et al.
Publicado: (2022)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
por: Ćorković, Ina, et al.
Publicado: (2022)

α-Glucosidase inhibitors and their use in clinical practice
por: Derosa, Giuseppe, et al.
Publicado: (2012)

α-Glucosidase Inhibitors from Vauquelinia corymbosa
por: Flores-Bocanegra, Laura, et al.
Publicado: (2015)

Characterizing the selectivity of ER α-glucosidase inhibitors
por: O’Keefe, Sarah, et al.
Publicado: (2019)

Flavonoids as Human Intestinal α-Glucosidase Inhibitors
por: Barber, Elizabeth, et al.
Publicado: (2021)

Indole-carbohydrazide linked phenoxy-1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro α-glucosidase inhibition, and computational studies
por: Emadi, Mehdi, et al.
Publicado: (2023)

Glycan–protein interactions determine kinetics of N-glycan remodeling
por: Mathew, Corina, et al.
Publicado: (2021)

An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications
por: Hossain, Uday, et al.
Publicado: (2020)

Identification of Cyclic Sulfonamides with an N-Arylacetamide Group as α-Glucosidase and α-Amylase Inhibitors: Biological Evaluation and Molecular Modeling
por: Saddique, Furqan Ahmad, et al.
Publicado: (2022)

Three New Acrylic Acid Derivatives from Achillea mellifolium as Potential Inhibitors of Urease from Jack Bean and α-Glucosidase from Saccharomyces cerevisiae
por: Farooq, Umar, et al.
Publicado: (2022)

QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors
por: Xu, Jun, et al.
Publicado: (2010)

α-Glucosidase inhibitors from the bark of Mangifera mekongensis
por: Nguyen, Hai Xuan, et al.
Publicado: (2016)

Untapped diamonds for untamed diabetes: The α-glucosidase inhibitors
por: Kalra, Sanjay, et al.
Publicado: (2014)

In Vitro and In Vivo Effects of Norathyriol and Mangiferin on α-Glucosidase
por: Shi, Zhi-Long, et al.
Publicado: (2017)

α-Glucosidase Inhibitory Activity of Selected Malaysian Plants
por: Mohd Bukhari, Dzatil Awanis, et al.
Publicado: (2017)

Effects of Synergistic Inhibition on α-glucosidase by Phytoalexins in Soybeans
por: Son, Hyeong-U, et al.
Publicado: (2019)

Correction to: Characterizing the selectivity of ER α-glucosidase inhibitors
Publicado: (2023)

Specific N-glycans of Hepatocellular Carcinoma Cell Surface and the Abnormal Increase of Core-α-1, 6-fucosylated Triantennary Glycan via N-acetylglucosaminyltransferases-IVa Regulation
por: Nie, Huan, et al.
Publicado: (2015)

Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein
por: Birol, Melissa, et al.
Publicado: (2019)

Design, Synthesis, and Activity Evaluation of Novel N-benzyl Deoxynojirimycin Derivatives for Use as α-Glucosidase Inhibitors
por: Zeng, Fanxin, et al.
Publicado: (2019)

Human FSH Glycoform α-Subunit Asparagine(52) Glycans: Major Glycan Structural Consistency, Minor Glycan Variation in Abundance
por: Butnev, Viktor Y., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lbi6qq3gr6u0686cidruef8ebq