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Evaluation of Interferon Resistance in Newly Established Genotype 1b Hepatitis C Virus Cell Culture System

Background and Aims: The hepatitis C virus (HCV) genotype 1b is known to exhibit treatment resistance with respect to interferon (IFN) therapy. Substitution of amino acids 70 and 91 in the core region of the 1b genotype is a significant predictor of liver carcinogenesis and poor response to pegylate...

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Detalles Bibliográficos
Autores principales:	Taniguchi, Miki, Tasaka-Fujita, Megumi, Nakagawa, Mina, Watanabe, Takako, Kawai-Kitahata, Fukiko, Otani, Satoshi, Goto, Fumio, Nagata, Hiroko, Kaneko, Shun, Nitta, Sayuri, Murakawa, Miyako, Nishimura-Sakurai, Yuki, Azuma, Seishin, Itsui, Yasuhiro, Mori, Kenichi, Yagi, Shintaro, Kakinuma, Sei, Asahina, Yasuhiro, Watanabe, Mamoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	XIA & HE Publishing Inc. 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807137/ https://www.ncbi.nlm.nih.gov/pubmed/27047766 http://dx.doi.org/10.14218/JCTH.2015.00047

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