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Proton-sensing GPCR-YAP Signalling Promotes Cancer-associated Fibroblast Activation of Mesenchymal Stem Cells

The pHs of extracellular fluids (ECFs) in normal tissues are commonly maintained at 7.35 to 7.45. The acidification of the ECF is one of the major characteristics of tumour microenvironment. In this study, we report that decreased extracellular pH promotes the transformation of mesenchymal stem cell...

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Detalles Bibliográficos
Autores principales:	Zhu, Hongyi, Guo, Shangchun, Zhang, Yuelei, Yin, Junhui, Yin, Wenjing, Tao, Shicong, Wang, Yang, Zhang, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807159/ https://www.ncbi.nlm.nih.gov/pubmed/27019624 http://dx.doi.org/10.7150/ijbs.13688

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