Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice

Inflammation-mediated abnormalities in the renin-angiotensin system (RAS) and expression of matrix metalloproteinases (MMPs) are implicated in the pathogenesis of lung injury. Angiotensin converting enzyme II (ACE2), an angiotensin converting enzyme (ACE) homologue that displays antagonist effects o...

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Detalles Bibliográficos
Autores principales: Hung, Yi-Han, Hsieh, Wen-Yeh, Hsieh, Jih-Sheng, Liu, Fon-Chang, Tsai, Chin-Hung, Lu, Li-Che, Huang, Chen-Yi, Wu, Chien-Liang, Lin, Chih-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807164/
https://www.ncbi.nlm.nih.gov/pubmed/27019629
http://dx.doi.org/10.7150/ijbs.13379

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