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PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM

Pseudomonas aeruginosa produces a number of alkylquinolone-type secondary metabolites best known for their antimicrobial effects and involvement in cell-cell communication. In the alkylquinolone biosynthetic pathway, the β-ketoacyl-(acyl carrier protein) synthase III (FabH)-like enzyme PqsBC catalyz...

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Detalles Bibliográficos
Autores principales:	Drees, Steffen Lorenz, Li, Chan, Prasetya, Fajar, Saleem, Muhammad, Dreveny, Ingrid, Williams, Paul, Hennecke, Ulrich, Emsley, Jonas, Fetzner, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807248/ https://www.ncbi.nlm.nih.gov/pubmed/26811339 http://dx.doi.org/10.1074/jbc.M115.708453

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