Cargando…

Tuning of Hemes b Equilibrium Redox Potential Is Not Required for Cross-Membrane Electron Transfer

In biological energy conversion, cross-membrane electron transfer often involves an assembly of two hemes b. The hemes display a large difference in redox midpoint potentials (ΔE(m_)b), which in several proteins is assumed to facilitate cross-membrane electron transfer and overcome a barrier of memb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pintscher, Sebastian, Kuleta, Patryk, Cieluch, Ewelina, Borek, Arkadiusz, Sarewicz, Marcin, Osyczka, Artur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Bioenergetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807273/ https://www.ncbi.nlm.nih.gov/pubmed/26858251 http://dx.doi.org/10.1074/jbc.M115.712307

Ejemplares similares

Mitochondrial Disease-related Mutation G167P in Cytochrome b of Rhodobacter capsulatus Cytochrome bc(1) (S151P in Human) Affects the Equilibrium Distribution of [2Fe-2S] Cluster and Generation of Superoxide
por: Borek, Arkadiusz, et al.
Publicado: (2015)

Demonstration of Short-lived Complexes of Cytochrome c with Cytochrome bc(1) by EPR Spectroscopy: IMPLICATIONS FOR THE MECHANISM OF INTERPROTEIN ELECTRON TRANSFER
por: Sarewicz, Marcin, et al.
Publicado: (2008)

Catalytically-relevant electron transfer between two hemes b(L) in the hybrid cytochrome bc(1)-like complex containing a fusion of Rhodobacter sphaeroides and capsulatus cytochromes b
por: Czapla, Monika, et al.
Publicado: (2013)

Visualizing changes in electron distribution in coupled chains of cytochrome bc(1) by modifying barrier for electron transfer between the FeS cluster and heme c(1)
por: Cieluch, Ewelina, et al.
Publicado: (2010)

Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc(1): Implications for the mechanism of superoxide production
por: Sarewicz, Marcin, et al.
Publicado: (2010)

A Pivotal Heme-transfer Reaction Intermediate in Cytochrome c Biogenesis
por: Mavridou, Despoina A. I., et al.
Publicado: (2012)

Hydrogen bonding rearrangement by a mitochondrial disease mutation in cytochrome bc(1) perturbs heme b(H) redox potential and spin state
por: Kuleta, Patryk, et al.
Publicado: (2021)

Identifying involvement of Lys251/Asp252 pair in electron transfer and associated proton transfer at the quinone reduction site of Rhodobacter capsulatus cytochrome bc(1)
por: Kuleta, Patryk, et al.
Publicado: (2016)

Enzymatic Activities of Isolated Cytochrome bc(1)-like Complexes Containing Fused Cytochrome b Subunits with Asymmetrically Inactivated Segments of Electron Transfer Chains
por: Czapla, Monika, et al.
Publicado: (2012)

The CcmC–CcmE interaction during cytochrome c maturation by System I is driven by protein–protein and not protein–heme contacts
por: Shevket, Shevket H., et al.
Publicado: (2018)

The High-Spin Heme b (L) Mutant Exposes Dominant Reaction Leading to the Formation of the Semiquinone Spin-Coupled to the [2Fe-2S](+) Cluster at the Q(o) Site of Rhodobacter capsulatus Cytochrome bc (1)
por: Sarewicz, Marcin, et al.
Publicado: (2021)

Identification of hydrogen bonding network for proton transfer at the quinol oxidation site of Rhodobacter capsulatus cytochrome bc(1)
por: Borek, Arkadiusz, et al.
Publicado: (2023)

Triplet State of the Semiquinone–Rieske Cluster as an Intermediate of Electronic Bifurcation Catalyzed by Cytochrome bc(1)
por: Sarewicz, Marcin, et al.
Publicado: (2013)

Unexpected Heme Redox Potential Values Implicate an Uphill Step in Cytochrome b(6)f
por: Szwalec, Mateusz, et al.
Publicado: (2022)

Superoxide Is Produced by the Reduced Flavin in Mitochondrial Complex I: A SINGLE, UNIFIED MECHANISM THAT APPLIES DURING BOTH FORWARD AND REVERSE ELECTRON TRANSFER
por: Pryde, Kenneth R., et al.
Publicado: (2011)

Modulation of Energy Transfer Pathways between Mitochondria and Myofibrils by Changes in Performance of Perfused Heart
por: Vendelin, Marko, et al.
Publicado: (2010)

NdhM Subunit Is Required for the Stability and the Function of NAD(P)H Dehydrogenase Complexes Involved in CO(2) Uptake in Synechocystis sp. Strain PCC 6803
por: He, Zhihui, et al.
Publicado: (2016)

Catalytic Reactions and Energy Conservation in the Cytochrome bc(1) and b(6)f Complexes of Energy-Transducing Membranes
por: Sarewicz, Marcin, et al.
Publicado: (2021)

Fusing two cytochromes b of Rhodobacter capsulatus cytochrome bc(1) using various linkers defines a set of protein templates for asymmetric mutagenesis
por: Czapla, Monika, et al.
Publicado: (2012)

Mitochondrial disease-related mutations at the cytochrome b-iron–sulfur protein (ISP) interface: Molecular effects on the large-scale motion of ISP and superoxide generation studied in Rhodobacter capsulatus cytochrome bc(1)()
por: Ekiert, Robert, et al.
Publicado: (2016)

Control of mitochondrial superoxide production by reverse electron transport at complex I
por: Robb, Ellen L., et al.
Publicado: (2018)

Effect of H bond removal and changes in the position of the iron–sulphur head domain on the spin–lattice relaxation properties of the [2Fe–2S](2+) Rieske cluster in cytochrome bc(1)
por: Sarewicz, Marcin, et al.
Publicado: (2015)

ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function
por: Darshi, Manjula, et al.
Publicado: (2011)

Menaquinone-7 Is Specific Cofactor in Tetraheme Quinol Dehydrogenase CymA
por: McMillan, Duncan G. G., et al.
Publicado: (2012)

Molecular Dynamics Simulations of Creatine Kinase and Adenine Nucleotide Translocase in Mitochondrial Membrane Patch
por: Karo, Jaanus, et al.
Publicado: (2012)

The Antisense RNA As1_flv4 in the Cyanobacterium Synechocystis sp. PCC 6803 Prevents Premature Expression of the flv4-2 Operon upon Shift in Inorganic Carbon Supply
por: Eisenhut, Marion, et al.
Publicado: (2012)

Reconstitution of Vacuolar-type Rotary H(+)-ATPase/Synthase from Thermus thermophilus
por: Kishikawa, Jun-ichi, et al.
Publicado: (2012)

The Deactive Form of Respiratory Complex I from Mammalian Mitochondria Is a Na(+)/H(+) Antiporter
por: Roberts, Philippa G., et al.
Publicado: (2012)

Functional Characterization of drim2, the Drosophila melanogaster Homolog of the Yeast Mitochondrial Deoxynucleotide Transporter
por: Da-Rè, Caterina, et al.
Publicado: (2014)

Leigh Syndrome in Drosophila melanogaster: MORPHOLOGICAL AND BIOCHEMICAL CHARACTERIZATION OF Surf1 POST-TRANSCRIPTIONAL SILENCING
por: Da-Rè, Caterina, et al.
Publicado: (2014)

Targeting and Import Mechanism of Coiled-coil Helix Coiled-coil Helix Domain-containing Protein 3 (ChChd3) into the Mitochondrial Intermembrane Space
por: Darshi, Manjula, et al.
Publicado: (2012)

Electrostatic Ratchet in the Protective Antigen Channel Promotes Anthrax Toxin Translocation
por: Wynia-Smith, Sarah L., et al.
Publicado: (2012)

Isolation and Characterization of a Hybrid Respiratory Supercomplex Consisting of Mycobacterium tuberculosis Cytochrome bcc and Mycobacterium smegmatis Cytochrome aa(3)*
por: Kim, Mi-Sun, et al.
Publicado: (2015)

Purification of Active Respiratory Supercomplex from Bovine Heart Mitochondria Enables Functional Studies
por: Shinzawa-Itoh, Kyoko, et al.
Publicado: (2016)

Trends in Thermostability Provide Information on the Nature of Substrate, Inhibitor, and Lipid Interactions with Mitochondrial Carriers
por: Crichton, Paul G., et al.
Publicado: (2015)

Post-translational Modifications near the Quinone Binding Site of Mammalian Complex I
por: Carroll, Joe, et al.
Publicado: (2013)

Meclizine Inhibits Mitochondrial Respiration through Direct Targeting of Cytosolic Phosphoethanolamine Metabolism
por: Gohil, Vishal M., et al.
Publicado: (2013)

NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I
por: Rhein, Virginie F., et al.
Publicado: (2016)

Lipid, Detergent, and Coomassie Blue G-250 Affect the Migration of Small Membrane Proteins in Blue Native Gels: MITOCHONDRIAL CARRIERS MIGRATE AS MONOMERS NOT DIMERS
por: Crichton, Paul G., et al.
Publicado: (2013)

Identification and quantification of protein S-nitrosation by nitrite in the mouse heart during ischemia
por: Chouchani, Edward T., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sbrqb3ckf9fsorremn1q02toi5