Cargando…

Glutathionylation of the Bacterial Hsp70 Chaperone DnaK Provides a Link between Oxidative Stress and the Heat Shock Response

DnaK is the major bacterial Hsp70, participating in DNA replication, protein folding, and the stress response. DnaK cooperates with the Hsp40 co-chaperone DnaJ and the nucleotide exchange factor GrpE. Under non-stress conditions, DnaK binds to the heat shock transcription factor σ(32) and facilitate...

Descripción completa

Detalles Bibliográficos
Autor principal:	Perrett, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807281/ https://www.ncbi.nlm.nih.gov/pubmed/26823468 http://dx.doi.org/10.1074/jbc.M115.673608

Ejemplares similares

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid
Publicado: (2020)

ATPase Activity and ATP-dependent Conformational Change in the Co-chaperone HSP70/HSP90-organizing Protein (HOP)
por: Yamamoto, Soh, et al.
Publicado: (2014)

A Platform to View Huntingtin Exon 1 Aggregation Flux in the Cell Reveals Divergent Influences from Chaperones hsp40 and hsp70
por: Ormsby, Angelique R., et al.
Publicado: (2013)

Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity
por: Rutsdottir, Gudrun, et al.
Publicado: (2017)

Human Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind Preferentially to the Disordered Conformation, Whereas Co-chaperone (HSC20) Binds to the Structured Conformation of the Iron-Sulfur Cluster Scaffold Protein (ISCU)
por: Cai, Kai, et al.
Publicado: (2013)

Specialized Hsp70 Chaperone (HscA) Binds Preferentially to the Disordered Form, whereas J-protein (HscB) Binds Preferentially to the Structured Form of the Iron-Sulfur Cluster Scaffold Protein (IscU)
por: Kim, Jin Hae, et al.
Publicado: (2012)

Primary Sequence That Determines the Functional Overlap between Mitochondrial Heat Shock Protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae
por: Pareek, Gautam, et al.
Publicado: (2011)

Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation
por: DeSantis, Morgan E., et al.
Publicado: (2014)

Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones
por: Rousseau, Erwann, et al.
Publicado: (2009)

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90
por: Cunningham, Christian N., et al.
Publicado: (2008)

Structural insight into proline cis/trans isomerization of unfolded proteins catalyzed by the trigger factor chaperone
por: Kawagoe, Soichiro, et al.
Publicado: (2018)

cpSRP43 Is a Novel Chaperone Specific for Light-harvesting Chlorophyll a,b-binding Proteins
por: Falk, Sebastian, et al.
Publicado: (2010)

Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions
por: Ortega-Roldan, Jose Luis, et al.
Publicado: (2013)

Ferredoxin Competes with Bacterial Frataxin in Binding to the Desulfurase IscS
por: Yan, Robert, et al.
Publicado: (2013)

Structural and Mechanistic Studies of Pesticin, a Bacterial Homolog of Phage Lysozymes
por: Patzer, Silke I., et al.
Publicado: (2012)

Structure of Signal-regulatory Protein α: A LINK TO ANTIGEN RECEPTOR EVOLUTION
por: Hatherley, Deborah, et al.
Publicado: (2009)

Olfactomedin-1 Has a V-shaped Disulfide-linked Tetrameric Structure
por: Pronker, Matti F., et al.
Publicado: (2015)

Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking
por: Lee, Jennifer, et al.
Publicado: (2015)

C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease
por: McGlinchey, Ryan P., et al.
Publicado: (2019)

Structural Insights into Higher Order Assembly and Function of the Bacterial Microcompartment Protein PduA
por: Pang, Allan, et al.
Publicado: (2014)

A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
por: Makowska-Grzyska, Magdalena, et al.
Publicado: (2015)

The S100A10-Annexin A2 Complex Provides a Novel Asymmetric Platform for Membrane Repair
por: Rezvanpour, Atoosa, et al.
Publicado: (2011)

Near-planar Solution Structures of Mannose-binding Lectin Oligomers Provide Insight on Activation of Lectin Pathway of Complement
por: Miller, Ami, et al.
Publicado: (2012)

Novel UDP-GalNAc Derivative Structures Provide Insight into the Donor Specificity of Human Blood Group Glycosyltransferase
por: Wagner, Gerd K., et al.
Publicado: (2015)

Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery
por: Schelpe, Julien, et al.
Publicado: (2016)

A Common Theme in Interaction of Bacterial Immunoglobulin-binding Proteins with Immunoglobulins Illustrated in the Equine System
por: Lewis, Melanie J., et al.
Publicado: (2008)

Defining Requirements for Collagenase Cleavage in Collagen Type III Using a Bacterial Collagen System
por: Yu, Zhuoxin, et al.
Publicado: (2012)

Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations
por: Hocking, Henry G., et al.
Publicado: (2008)

Crystal Structure of SmcR, a Quorum-sensing Master Regulator of Vibrio vulnificus, Provides Insight into Its Regulation of Transcription
por: Kim, Yoonjeong, et al.
Publicado: (2010)

Uncovering the Early Assembly Mechanism for Amyloidogenic β(2)-Microglobulin Using Cross-linking and Native Mass Spectrometry
por: Hall, Zoe, et al.
Publicado: (2016)

The structure of the bacterial iron–catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism
por: Grinter, Rhys, et al.
Publicado: (2019)

Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor
por: Hwang, Jungwon, et al.
Publicado: (2011)

Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer
por: Pedrote, Murilo M., et al.
Publicado: (2018)

Six-transmembrane Topology for Golgi Anti-apoptotic Protein (GAAP) and Bax Inhibitor 1 (BI-1) Provides Model for the Transmembrane Bax Inhibitor-containing Motif (TMBIM) Family
por: Carrara, Guia, et al.
Publicado: (2012)

X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions
por: Chen, Yafang, et al.
Publicado: (2015)

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3
por: Esposito, Diego, et al.
Publicado: (2018)

Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK
por: Dias, Marcio V. B., et al.
Publicado: (2010)

Mechanism of Histone H3K4me3 Recognition by the Plant Homeodomain of Inhibitor of Growth 3
por: Kim, Sophia, et al.
Publicado: (2016)

Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance
por: Das, Kalyan, et al.
Publicado: (2009)

Development of Fluorescence Polarization Assays for the Molecular Chaperone Hsp70 Family Members: Hsp72 and DnaK
por: Ricci, Laura, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_g6poklfs6ev2qts88c5g8rub9n