Cargando…

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

Infection with human cytomegalovirus (HCMV) profoundly affects cellular metabolism. Like in tumor cells, HCMV infection increases glycolysis, and glucose carbon is shifted from the mitochondrial tricarboxylic acid cycle to the biosynthesis of fatty acids. However, unlike in many tumor cells, where a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karniely, S., Weekes, M. P., Antrobus, R., Rorbach, J., van Haute, L., Umrania, Y., Smith, D. L., Stanton, R. J., Minczuk, M., Lehner, P. J., Sinclair, J. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807356/ https://www.ncbi.nlm.nih.gov/pubmed/27025248 http://dx.doi.org/10.1128/mBio.00029-16

Ejemplares similares

PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria
por: Rorbach, Joanna, et al.
Publicado: (2011)

Human Cytomegalovirus RNA2.7 Is Required for Upregulating Multiple Cellular Genes To Promote Cell Motility and Viral Spread Late in Lytic Infection
por: Lau, Betty, et al.
Publicado: (2021)

Alternative translation initiation augments the human mitochondrial proteome
por: Kazak, Lawrence, et al.
Publicado: (2013)

Mitochondrial transcription and translation: overview
por: D’Souza, Aaron R., et al.
Publicado: (2018)

Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
por: Fletcher-Etherington, Alice, et al.
Publicado: (2020)

Mitochondrial transcript maturation and its disorders
por: Van Haute, Lindsey, et al.
Publicado: (2015)

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome
por: Rorbach, Joanna, et al.
Publicado: (2012)

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome
por: Rorbach, Joanna, et al.
Publicado: (2016)

Human mitochondrial ribosomes can switch structural tRNAs – but when and why?
por: Chrzanowska-Lightowlers, Zofia, et al.
Publicado: (2017)

Maturation of selected human mitochondrial tRNAs requires deadenylation
por: Pearce, Sarah F, et al.
Publicado: (2017)

Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations
por: Gammage, Payam A, et al.
Publicado: (2014)

High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms
por: Nightingale, Katie, et al.
Publicado: (2018)

Human cytomegalovirus: taking the strain
por: Wilkinson, Gavin W. G., et al.
Publicado: (2015)

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery
por: Peeva, Viktoriya, et al.
Publicado: (2018)

Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation
por: Lau, Betty, et al.
Publicado: (2020)

The mammalian mitochondrial epitranscriptome()
por: Rebelo-Guiomar, Pedro, et al.
Publicado: (2019)

Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
por: Nobre, Luis V, et al.
Publicado: (2019)

Mitochondrial translation initiation machinery: Conservation and diversification()
por: Kuzmenko, Anton, et al.
Publicado: (2014)

Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation
por: Fielding, Ceri A., et al.
Publicado: (2014)

Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation
por: Fielding, Ceri A, et al.
Publicado: (2017)

Dealing with an Unconventional Genetic Code in Mitochondria: The Biogenesis and Pathogenic Defects of the 5-Formylcytosine Modification in Mitochondrial tRNA(Met)
por: Van Haute, Lindsey, et al.
Publicado: (2017)

Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor
por: Perera, Marianne R, et al.
Publicado: (2022)

Plasma Membrane Profiling Reveals Upregulation of ABCA1 by Infected Macrophages Leading to Restriction of Mycobacterial Growth
por: Long, Jing, et al.
Publicado: (2016)

Temporal Proteomic Analysis of BK Polyomavirus Infection Reveals Virus-Induced G(2) Arrest and Highly Effective Evasion of Innate Immune Sensing
por: Caller, Laura G., et al.
Publicado: (2019)

The mitochondrial transcription machinery genes are upregulated in acute myeloid leukemia and associated with poor clinical outcome
por: Wu, Sharon, et al.
Publicado: (2019)

Human Cytomegalovirus Upregulates Expression of HCLS1 Resulting in Increased Cell Motility and Transendothelial Migration during Latency
por: Aslam, Yusuf, et al.
Publicado: (2019)

YbeY is required for ribosome small subunit assembly and tRNA processing in human mitochondria
por: D’Souza, Aaron R, et al.
Publicado: (2021)

Virus-Mediated Compartmentalization of the Host Translational Machinery
por: Desmet, Emily A., et al.
Publicado: (2014)

Strategies for in vitro engineering of the translation machinery
por: Hammerling, Michael J, et al.
Publicado: (2020)

Regulation of Mammalian Mitochondrial Gene Expression: Recent Advances
por: Pearce, Sarah F., et al.
Publicado: (2017)

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas
por: D'Andrea, Aleco, et al.
Publicado: (2016)

MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome
por: Rorbach, Joanna, et al.
Publicado: (2014)

Epigenetic Regulation of the Protein Translation Machinery
por: Holland, Michelle L
Publicado: (2017)

Quantitative density gradient analysis by mass spectrometry (qDGMS) and complexome profiling analysis (ComPrAn) R package for the study of macromolecular complexes
por: Páleníková, Petra, et al.
Publicado: (2021)

Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6
por: Weekes, Michael P., et al.
Publicado: (2012)

Haploid Genetic Screens Identify an Essential Role for PLP2 in the Downregulation of Novel Plasma Membrane Targets by Viral E3 Ubiquitin Ligases
por: Timms, Richard T., et al.
Publicado: (2013)

Inactivation of group 2 σ factors upregulates production of transcription and translation machineries in the cyanobacterium Synechocystis sp. PCC 6803
por: Koskinen, Satu, et al.
Publicado: (2018)

Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations
por: Hoitzing, Hanne, et al.
Publicado: (2019)

Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
por: Ho, J.J. David, et al.
Publicado: (2021)

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex
por: Nightingale, Katie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8gee3n7je4rhc9ukdt0470vihj