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Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation

Simian virus 40 (SV40), a polyomavirus that has served as an important model to understand many aspects of biology, induces dramatic cytoplasmic vacuolization late during productive infection of monkey host cells. Although this activity led to the discovery of the virus in 1960, the mechanism of vac...

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Detalles Bibliográficos
Autores principales: Luo, Yong, Motamedi, Nasim, Magaldi, Thomas G., Gee, Gretchen V., Atwood, Walter J., DiMaio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807364/
https://www.ncbi.nlm.nih.gov/pubmed/27006465
http://dx.doi.org/10.1128/mBio.00297-16

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