Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs

Directed differentiation of human induced pluripotent stem cells (iPSCs) into retinal pigmented epithelium (RPE) holds great promise in cell replacement therapy for patients suffering from degenerative eye diseases, including age-related macular degeneration (AMD). In this study, we generated iPSCs...

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Detalles Bibliográficos
Autores principales: Li, Peng, Sun, Xiaofeng, Ma, Zhizhong, Liu, Yinan, Jin, Ying, Ge, Ruimin, Hao, Limin, Ma, Yanling, Han, Shuo, Sun, Haojie, Zhang, Mingzhi, Li, Ruizhi, Li, Tao, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807412/
https://www.ncbi.nlm.nih.gov/pubmed/27019633
http://dx.doi.org/10.7150/ijbs.14212

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