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High-content screening identifies a role for Na(+) channels in insulin production
Insulin production is the central feature of functionally mature and differentiated pancreatic β-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse these processes potentially useful. We have previously established rati...
Autores principales: | Szabat, Marta, Modi, Honey, Ramracheya, Reshma, Girbinger, Vroni, Chan, Forson, Lee, Jason T. C., Piske, Micah, Kamal, Sepehr, Carol Yang, Yu Hsuan, Welling, Andrea, Rorsman, Patrik, Johnson, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807443/ https://www.ncbi.nlm.nih.gov/pubmed/27019722 http://dx.doi.org/10.1098/rsos.150306 |
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