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YAP Induces Human Naive Pluripotency

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in...

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Detalles Bibliográficos
Autores principales:	Qin, Han, Hejna, Miroslav, Liu, Yanxia, Percharde, Michelle, Wossidlo, Mark, Blouin, Laure, Durruthy-Durruthy, Jens, Wong, Priscilla, Qi, Zhongxia, Yu, Jingwei, Qi, Lei S., Sebastiano, Vittorio, Song, Jun S., Ramalho-Santos, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807727/ https://www.ncbi.nlm.nih.gov/pubmed/26947063 http://dx.doi.org/10.1016/j.celrep.2016.02.036

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