Development of an HPLC Method with an ODS Column to Determine Low Levels of Aspartame Diastereomers in Aspartame

α-L-Aspartyl-D-phenylalanine methyl ester (L, D-APM) and α-D-aspartyl-L-phenylalanine methyl ester (D, L-APM) are diastereomers of aspartame (N-L-α-Aspartyl-L-phenylalanine-1-methyl ester, L, L-APM). The Joint FAO/WHO Expert Committee on Food Additives has set 0.04 wt% as the maximum permitted level...

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Detalles Bibliográficos
Autores principales: Ohtsuki, Takashi, Nakamura, Ryoichiro, Kubo, Satoru, Otabe, Akira, Oobayashi, Yoko, Suzuki, Shoko, Yoshida, Mika, Yoshida, Mitsuya, Tatebe, Chiye, Sato, Kyoko, Akiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807810/
https://www.ncbi.nlm.nih.gov/pubmed/27015640
http://dx.doi.org/10.1371/journal.pone.0152174

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