Cargando…

Evaluation of mRNA Biomarkers to Identify Risk of Hospital Acquired Infections in Children Admitted to Paediatric Intensive Care Unit

OBJECTIVES: Hospital-acquired infections (HAI) are associated with significant mortality and morbidity and prolongation of hospital stay, adding strain on limited hospital resources. Despite stringent infection control practices some children remain at high risk of developing HAI. The development of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peronnet, Estelle, Nguyen, Kha, Cerrato, Elisabeth, Guhadasan, Rathi, Venet, Fabienne, Textoris, Julien, Pachot, Alexandre, Monneret, Guillaume, Carrol, Enitan Delphine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807819/ https://www.ncbi.nlm.nih.gov/pubmed/27015534 http://dx.doi.org/10.1371/journal.pone.0152388

Ejemplares similares

Low Interleukin-7 Receptor Messenger RNA Expression Is Independently Associated With Day 28 Mortality in Septic Shock Patients*
por: Delwarde, Benjamin, et al.
Publicado: (2018)

Altered T Lymphocyte Proliferation upon Lipopolysaccharide Challenge Ex Vivo
por: Poujol, Fanny, et al.
Publicado: (2015)

Association between mRNA expression of CD74 and IL10 and risk of ICU-acquired infections: a multicenter cohort study
por: Peronnet, Estelle, et al.
Publicado: (2017)

S100A8/A9 mRNA Induction in an Ex Vivo Model of Endotoxin Tolerance: Roles of IL-10 and IFNγ
por: Fontaine, Mathieu, et al.
Publicado: (2014)

Regulation of soluble CD127 protein release and corresponding transcripts expression in T lymphocytes from septic shock patients
por: Mouillaux, Julie, et al.
Publicado: (2019)

mRNA-based approach to monitor recombinant gamma-interferon restoration of LPS-induced endotoxin tolerance
por: Turrel-Davin, Fanny, et al.
Publicado: (2011)

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn
por: Tabone, Olivier, et al.
Publicado: (2019)

Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock
por: Cazalis, Marie-Angélique, et al.
Publicado: (2013)

TCR activation mimics CD127(low)PD-1(high) phenotype and functional alterations of T lymphocytes from septic shock patients
por: Mouillaux, Julie, et al.
Publicado: (2019)

Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial
por: Plassais, Jonathan, et al.
Publicado: (2017)

Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study
por: Peronnet, Estelle, et al.
Publicado: (2023)

Dynamic LTR retrotransposon transcriptome landscape in septic shock patients
por: Mommert, Marine, et al.
Publicado: (2020)

Intra-cellular lactate concentration in T lymphocytes from septic shock patients — a pilot study
por: Girardot, Thibaut, et al.
Publicado: (2018)

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs
por: Mommert, Marine, et al.
Publicado: (2018)

Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score
por: Bodinier, Maxime, et al.
Publicado: (2023)

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients
por: Bodinier, Maxime, et al.
Publicado: (2021)

Low-dose hydrocortisone reduces norepinephrine duration in severe burn patients: a randomized clinical trial
por: Venet, Fabienne, et al.
Publicado: (2015)

The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients
por: Rol, Mary-Luz, et al.
Publicado: (2017)

Decreased expression of HLA-DR antigen-associated invariant chain mRNA predicts mortality after septic shock
por: Cazalis, M-A, et al.
Publicado: (2012)

Assessment of sepsis-induced immunosuppression at ICU discharge and 6 months after ICU discharge
por: Zorio, Violette, et al.
Publicado: (2017)

0041. The effect of low-dose hydrocortisone after severe burn injury: a microarray longitudinal study
por: Textoris, J, et al.
Publicado: (2014)

Correction: Identification of Biomarkers of Response to IFNg during Endotoxin Tolerance: Application to Septic Shock
por: Allantaz-Frager, Florence, et al.
Publicado: (2013)

Identification of Biomarkers of Response to IFNg during Endotoxin Tolerance: Application to Septic Shock
por: Allantaz-Frager, Florence, et al.
Publicado: (2013)

Delayed increased S100A9 mRNA predicts hospital-acquired infection after septic shock
por: Fontaine, M, et al.
Publicado: (2009)

Mortality Prediction in Sepsis With an Immune-Related Transcriptomics Signature: A Multi-Cohort Analysis
por: Kreitmann, Louis, et al.
Publicado: (2022)

Interferon gamma as an immune modulating adjunct therapy for invasive mucormycosis after severe burn – A case report
por: Tawfik, Dina M., et al.
Publicado: (2022)

Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
por: de Roquetaillade, Charles, et al.
Publicado: (2019)

Deciphering heterogeneity of septic shock patients using immune functional assays: a proof of concept study
por: Albert Vega, Chloé, et al.
Publicado: (2020)

Additional bad news from regulatory T cells in sepsis
por: Monneret, Guillaume, et al.
Publicado: (2010)

A rapidly progressing lymphocyte exhaustion after severe sepsis
por: Monneret, Guillaume, et al.
Publicado: (2012)

Monocyte HLA-DR in sepsis: shall we stop following the flow?
por: Monneret, Guillaume, et al.
Publicado: (2014)

A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates
por: Tournoud, Maud, et al.
Publicado: (2015)

PSP/reg and NT-proCNP to predict the occurrence of ICU-acquired sepsis in severe trauma patients: results of a pilot study
por: Dupin, M, et al.
Publicado: (2012)

Concomitant assessment of PSP and NT-proCNP as predictive markers of sepsis in severe trauma patients under mechanical ventilation
por: Gouel-Chéron, Aurélie, et al.
Publicado: (2013)

Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach
por: Cazalis, Marie-Angélique, et al.
Publicado: (2014)

Early herpes and TTV DNAemia in septic shock patients: a pilot study
por: Mallet, François, et al.
Publicado: (2019)

Immune Profiling Panel: A Proof-of-Concept Study of a New Multiplex Molecular Tool to Assess the Immune Status of Critically Ill Patients
por: Tawfik, Dina M, et al.
Publicado: (2020)

Comparison of host immune responses to LPS in human using an immune profiling panel, in vivo endotoxemia versus ex vivo stimulation
por: Tawfik, Dina M., et al.
Publicado: (2020)

A dynamic view of mHLA-DR expression in management of severe septic patients
por: Monneret, Guillaume, et al.
Publicado: (2011)

Clinical review: flow cytometry perspectives in the ICU - from diagnosis of infection to monitoring of injury-induced immune dysfunctions
por: Venet, Fabienne, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0upda9lo9rf4ma5u3lul014lt5