Cargando…

miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis

Mesenchymal Stromal/Stem Cells (MSC) are currently being explored in diverse clinical applications, including regenerative therapies. Their contribution to regeneration of bone fractures is dependent on their capacity to proliferate, undergo osteogenesis and induce angiogenesis. This study aimed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almeida, Maria Ines, Silva, Andreia Machado, Vasconcelos, Daniel Marques, Almeida, Catarina Rodrigues, Caires, Hugo, Pinto, Marta Teixeira, Calin, George Adrian, Santos, Susana Gomes, Barbosa, Mário Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807979/ https://www.ncbi.nlm.nih.gov/pubmed/26683705

Ejemplares similares

Local injection of high-molecular hyaluronan promotes wound healing in old rats by increasing angiogenesis
por: Huang, Luying, et al.
Publicado: (2017)

Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
por: Özcan, Servet, et al.
Publicado: (2015)

Ginsenoside Rg3 inhibits the senescence of prostate stromal cells through down-regulation of interleukin 8 expression
por: Peng, Yanfei, et al.
Publicado: (2017)

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells
por: Capasso, Stefania, et al.
Publicado: (2015)

Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis
por: O'Hagan-Wong, Kelsey, et al.
Publicado: (2016)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Rapid and simple detection of gero-suppressive agents
por: Darzynkiewicz, Zbigniew
Publicado: (2015)

WW domain-containing oxidoreductase in neuronal injury and neurological diseases
por: Chang, Hsin-Tzu, et al.
Publicado: (2014)

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition
por: Rémond, Didier, et al.
Publicado: (2015)

Measuring refractive index distribution in the human eye lens
por: Pope, James M., et al.
Publicado: (2015)

Characterization and redox mechanism of asthma in the elderly
por: Zuo, Li, et al.
Publicado: (2016)

REM sleep behaviour disorder (RBD): risk for Parkinsonism and executive dysfunction in elderly
por: Lerche, Stefanie, et al.
Publicado: (2018)

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
por: Li, Guihua, et al.
Publicado: (2016)

Reprogramming of energy metabolism as a driver of aging
por: Feng, Zhaoyang, et al.
Publicado: (2016)

miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells
por: Bras, Joao Paulo, et al.
Publicado: (2017)

Long-term monitoring of Ca(2+) dynamics in C. elegans pharynx: an in vivo energy balance sensor
por: Alvarez-Illera, Pilar, et al.
Publicado: (2016)

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons
por: Vezzali, Riccardo, et al.
Publicado: (2016)

Effect of the diet type and temperature on the C. elegans transcriptome
por: Gómez-Orte, Eva, et al.
Publicado: (2017)

Interferon-gamma deficiency protects against aging-related goblet cell loss
por: Volpe, Eugene A., et al.
Publicado: (2016)

The effect of D-serine administration on cognition and mood in older adults
por: Avellar, Marcos, et al.
Publicado: (2016)

Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes
por: Kreienkamp, Ray, et al.
Publicado: (2016)

Genome-wide significant risk factors on chromosome 19 and the APOE locus
por: Moreno-Grau, Sonia, et al.
Publicado: (2018)

Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cells
por: Løhr, Mille, et al.
Publicado: (2014)

Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain
por: Chang, Jean-Yun, et al.
Publicado: (2015)

Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent
por: Sabbieti, Maria Giovanna, et al.
Publicado: (2015)

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival
por: Kim, Sangkyu, et al.
Publicado: (2015)

The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
por: Ramdzan, Zubaidah M., et al.
Publicado: (2015)

DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3ʹ-end GC density
por: Yu, Bo, et al.
Publicado: (2015)

Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells
por: Tsuchihashi, Nana Akagi, et al.
Publicado: (2014)

Ammonium is a key determinant on the dietary restriction of yeast chronological aging in culture medium
por: Santos, Júlia, et al.
Publicado: (2014)

Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors
por: Corsini, Emanuela, et al.
Publicado: (2015)

Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal
por: Yousef, Hanadie, et al.
Publicado: (2015)

Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies
por: Burks, Tyesha N., et al.
Publicado: (2015)

EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells
por: Lee, Ju-Hee, et al.
Publicado: (2015)

Rapatar, a nanoformulation of rapamycin, decreases chemically-induced benign prostate hyperplasia in rats
por: Lesovaya, Ekaterina A., et al.
Publicado: (2015)

New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor
por: Kanashiro-Takeuchi, Rosemeire M., et al.
Publicado: (2015)

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes
por: Chen, Yng-Tay, et al.
Publicado: (2015)

MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts
por: Liao, Po-Hsiang, et al.
Publicado: (2015)

Association between serum uric acid and bone health in general population: a large and multicentre study
por: Lin, Xianfeng, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_08d6vch5jt8jrspae674fl64ta