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GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells
Aldosterone induces relevant effects binding to the mineralcorticoid receptor (MR), which acts as a ligand-gated transcription factor. Alternate mechanisms can mediate the action of aldosterone such as the activation of epidermal growth factor receptor (EGFR), MAPK/ERK, transcription factors and ion...
Autores principales: | Rigiracciolo, Damiano Cosimo, Scarpelli, Andrea, Lappano, Rosamaria, Pisano, Assunta, Santolla, Maria Francesca, Avino, Silvia, De Marco, Paola, Bussolati, Benedetta, Maggiolini, Marcello, De Francesco, Ernestina Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807985/ https://www.ncbi.nlm.nih.gov/pubmed/26646587 |
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