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Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition

Recent clinical data indicate a synergistic therapeutic effect between trastuzumab and taxanes in neoadjuvantly treated HER2-positive breast cancer (BC) patients. In HER2+ BC experimental models and patients, we investigated whether this synergy depends on the ability of drug-induced stress to impro...

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Detalles Bibliográficos
Autores principales:	Di Modica, Martina, Sfondrini, Lucia, Regondi, Viola, Varchetta, Stefania, Oliviero, Barbara, Mariani, Gabriella, Bianchi, Giulia Valeria, Generali, Daniele, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807996/ https://www.ncbi.nlm.nih.gov/pubmed/26595802

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