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An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer

In human cancer, high telomerase expression is correlated with tumor aggressiveness and metastatic potential. Telomerase activation occurs through telomerase reverse transcriptase (hTERT) induction, which contributes to malignant transformation by stabilizing telomeres. Previous studies have shown t...

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Detalles Bibliográficos
Autores principales: Qin, Yong, Tang, Bo, Hu, Chang-Jiang, Xiao, Yu-Feng, Xie, Rui, Yong, Xin, Wu, Yu-Yun, Dong, Hui, Yang, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808003/
https://www.ncbi.nlm.nih.gov/pubmed/26540342

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