The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer

A common single-nucleotide polymorphism in the telomerase reverse transcriptase (TERT) promoter, rs2853669 influences patient survival rates and the risk of developing cancer. Recently, several lines of evidence suggest that the rs2853669 suppresses TERT promoter mutation-mediated TERT expression le...

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Detalles Bibliográficos
Autores principales: Ko, Eunkyong, Seo, Hyun-Wook, Jung, Eun Sun, Kim, Baek-hui, Jung, Guhung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808026/
https://www.ncbi.nlm.nih.gov/pubmed/26575952

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