Cargando…
Auranofin is a potent suppressor of osteosarcoma metastasis
Osteosarcoma (OS) accounts for 56% of malignant bone cancers in children and adolescents. Patients with localized disease rarely develop metastasis; however, pulmonary metastasis occurs in approximately 50% of patients and leads to a 5-year survival rate of only 10–20%. Therefore, identifying the ge...
Autores principales: | Topkas, Eleni, Cai, Na, Cumming, Andrew, Hazar-Rethinam, Mehlika, Gannon, Orla Margaret, Burgess, Melinda, Saunders, Nicholas Andrew, Endo-Munoz, Liliana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808036/ https://www.ncbi.nlm.nih.gov/pubmed/26573231 |
Ejemplares similares
-
Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis
por: Cameron, Sarina, et al.
Publicado: (2012) -
The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis
por: Hazar-Rethinam, Mehlika, et al.
Publicado: (2011) -
Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis
por: Endo-Munoz, Liliana, et al.
Publicado: (2015) -
Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones
por: Macklin, Rebecca, et al.
Publicado: (2016) -
Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone
por: Endo-Munoz, L, et al.
Publicado: (2010)