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Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases

Coronary atherothrombotic diseases such as coronary artery disease, peripheral vascular disease, cerebrovascular disease, and heart failure are the serious concerns of the thrombus formed in blood vessels. Anticoagulant and antiplatelet drugs are the cornerstones of the management of these diseases....

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Autores principales: Mohd Nor, Nurul Huda, Othman, Fauziah, Mohd Tohit, Eusni Rahayu, Md Noor, Sabariah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808659/
https://www.ncbi.nlm.nih.gov/pubmed/27051529
http://dx.doi.org/10.1155/2016/5952910
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author Mohd Nor, Nurul Huda
Othman, Fauziah
Mohd Tohit, Eusni Rahayu
Md Noor, Sabariah
author_facet Mohd Nor, Nurul Huda
Othman, Fauziah
Mohd Tohit, Eusni Rahayu
Md Noor, Sabariah
author_sort Mohd Nor, Nurul Huda
collection PubMed
description Coronary atherothrombotic diseases such as coronary artery disease, peripheral vascular disease, cerebrovascular disease, and heart failure are the serious concerns of the thrombus formed in blood vessels. Anticoagulant and antiplatelet drugs are the cornerstones of the management of these diseases. To prevent the recurrence of these diseases, double antiplatelet drugs such as aspirin and clopidogrel has been the standard management in most hospitals. However, aspirin resistance and clopidogrel inefficient effects due to noncompliance with double drugs regimen can cause a sinister effect on patients. Medicinal plants serve as a greater resource for new medication and their potential currently became a topic of interest to the researchers all over the world. Traditionally, certain herbs have been used as a treatment for heart diseases but have been investigated for their antiplatelet properties. This current review explained few traditional antithrombotic herbals and their antiplatelet properties in vitro and in vivo and this is to be deeply discussed in further research.
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spelling pubmed-48086592016-04-05 Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases Mohd Nor, Nurul Huda Othman, Fauziah Mohd Tohit, Eusni Rahayu Md Noor, Sabariah Thrombosis Review Article Coronary atherothrombotic diseases such as coronary artery disease, peripheral vascular disease, cerebrovascular disease, and heart failure are the serious concerns of the thrombus formed in blood vessels. Anticoagulant and antiplatelet drugs are the cornerstones of the management of these diseases. To prevent the recurrence of these diseases, double antiplatelet drugs such as aspirin and clopidogrel has been the standard management in most hospitals. However, aspirin resistance and clopidogrel inefficient effects due to noncompliance with double drugs regimen can cause a sinister effect on patients. Medicinal plants serve as a greater resource for new medication and their potential currently became a topic of interest to the researchers all over the world. Traditionally, certain herbs have been used as a treatment for heart diseases but have been investigated for their antiplatelet properties. This current review explained few traditional antithrombotic herbals and their antiplatelet properties in vitro and in vivo and this is to be deeply discussed in further research. Hindawi Publishing Corporation 2016 2016-03-14 /pmc/articles/PMC4808659/ /pubmed/27051529 http://dx.doi.org/10.1155/2016/5952910 Text en Copyright © 2016 Nurul Huda Mohd Nor et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mohd Nor, Nurul Huda
Othman, Fauziah
Mohd Tohit, Eusni Rahayu
Md Noor, Sabariah
Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title_full Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title_fullStr Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title_full_unstemmed Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title_short Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases
title_sort medicinal herbals with antiplatelet properties benefit in coronary atherothrombotic diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808659/
https://www.ncbi.nlm.nih.gov/pubmed/27051529
http://dx.doi.org/10.1155/2016/5952910
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