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Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat
Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), i...
Autores principales: | Jacome-Sosa, Miriam, Vacca, Claudia, Mangat, Rabban, Diane, Abdoulaye, Nelson, Randy C., Reaney, Martin J., Shen, Jianheng, Curtis, Jonathan M., Vine, Donna F., Field, Catherine J., Igarashi, Miki, Piomelli, Daniele, Banni, Sebastiano, Proctor, Spencer D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808772/ https://www.ncbi.nlm.nih.gov/pubmed/26891736 http://dx.doi.org/10.1194/jlr.M066308 |
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