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Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia

Iodine deficiency disorders are estimated to affect over 1.9 million people worldwide. Iodine deficiency is especially serious for women during pregnancy and lactation because of the negative consequences for both mother and infant. The aim of this cross-sectional study was to determine the median u...

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Autores principales: Karakochuk, Crystal D., Michaux, Kristina D., Chai, Tze L., Chan, Benny B., Whitfield, Kyly C., Barr, Susan I., McLean, Judy, Talukder, Aminuzzaman, Hou, Kroeun, Ly, Sokhoing, Green, Tim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808868/
https://www.ncbi.nlm.nih.gov/pubmed/26950151
http://dx.doi.org/10.3390/nu8030139
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author Karakochuk, Crystal D.
Michaux, Kristina D.
Chai, Tze L.
Chan, Benny B.
Whitfield, Kyly C.
Barr, Susan I.
McLean, Judy
Talukder, Aminuzzaman
Hou, Kroeun
Ly, Sokhoing
Green, Tim J.
author_facet Karakochuk, Crystal D.
Michaux, Kristina D.
Chai, Tze L.
Chan, Benny B.
Whitfield, Kyly C.
Barr, Susan I.
McLean, Judy
Talukder, Aminuzzaman
Hou, Kroeun
Ly, Sokhoing
Green, Tim J.
author_sort Karakochuk, Crystal D.
collection PubMed
description Iodine deficiency disorders are estimated to affect over 1.9 million people worldwide. Iodine deficiency is especially serious for women during pregnancy and lactation because of the negative consequences for both mother and infant. The aim of this cross-sectional study was to determine the median urinary iodine concentration (UIC) as a population-level indicator of iodine status among rural women farmers of reproductive age (18–45 years) in the province of Prey Veng, Cambodia. A total of 450 women provided a spot morning urine sample in 2012. Of those women, 93% (n = 420) were non-pregnant and 7% (n = 30) were pregnant at the time of collection. UIC was quantified using the Sandell-Kolthoff reaction with modifications. The median UIC of non-pregnant (139 μg/L) and pregnant women (157 μg/L) were indicative of adequate iodine status using the WHO/UNICEF/ICCIDD epidemiological criteria for both groups (median UIC between 100–199 and 150–249 μg/L, respectively). We conclude that non-pregnant and pregnant women in rural Prey Veng, Cambodia had adequate iodine status based on single spot morning urine samples collected in 2012. More research is warranted to investigate iodine status among larger and more representative populations of women in Cambodia, especially in light of recent policy changes to the national program for universal salt iodization.
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spelling pubmed-48088682016-04-04 Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia Karakochuk, Crystal D. Michaux, Kristina D. Chai, Tze L. Chan, Benny B. Whitfield, Kyly C. Barr, Susan I. McLean, Judy Talukder, Aminuzzaman Hou, Kroeun Ly, Sokhoing Green, Tim J. Nutrients Article Iodine deficiency disorders are estimated to affect over 1.9 million people worldwide. Iodine deficiency is especially serious for women during pregnancy and lactation because of the negative consequences for both mother and infant. The aim of this cross-sectional study was to determine the median urinary iodine concentration (UIC) as a population-level indicator of iodine status among rural women farmers of reproductive age (18–45 years) in the province of Prey Veng, Cambodia. A total of 450 women provided a spot morning urine sample in 2012. Of those women, 93% (n = 420) were non-pregnant and 7% (n = 30) were pregnant at the time of collection. UIC was quantified using the Sandell-Kolthoff reaction with modifications. The median UIC of non-pregnant (139 μg/L) and pregnant women (157 μg/L) were indicative of adequate iodine status using the WHO/UNICEF/ICCIDD epidemiological criteria for both groups (median UIC between 100–199 and 150–249 μg/L, respectively). We conclude that non-pregnant and pregnant women in rural Prey Veng, Cambodia had adequate iodine status based on single spot morning urine samples collected in 2012. More research is warranted to investigate iodine status among larger and more representative populations of women in Cambodia, especially in light of recent policy changes to the national program for universal salt iodization. MDPI 2016-03-03 /pmc/articles/PMC4808868/ /pubmed/26950151 http://dx.doi.org/10.3390/nu8030139 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Karakochuk, Crystal D.
Michaux, Kristina D.
Chai, Tze L.
Chan, Benny B.
Whitfield, Kyly C.
Barr, Susan I.
McLean, Judy
Talukder, Aminuzzaman
Hou, Kroeun
Ly, Sokhoing
Green, Tim J.
Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title_full Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title_fullStr Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title_full_unstemmed Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title_short Median Urinary Iodine Concentrations Are Indicative of Adequate Iodine Status among Women of Reproductive Age in Prey Veng, Cambodia
title_sort median urinary iodine concentrations are indicative of adequate iodine status among women of reproductive age in prey veng, cambodia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808868/
https://www.ncbi.nlm.nih.gov/pubmed/26950151
http://dx.doi.org/10.3390/nu8030139
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