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Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells
Sirt1 is a NAD(+)-dependent protein-modifying enzyme involved in regulating gene expression, DNA damage repair, metabolism and survival, as well as acts as an important subcellular target of resveratrol. The complex mechanisms underlying Sirt1 signaling during carcinogenesis remain controversial, as...
Autores principales: | Buhrmann, Constanze, Shayan, Parviz, Popper, Bastian, Goel, Ajay, Shakibaei, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808874/ https://www.ncbi.nlm.nih.gov/pubmed/26959057 http://dx.doi.org/10.3390/nu8030145 |
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