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Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells

Sirt1 is a NAD(+)-dependent protein-modifying enzyme involved in regulating gene expression, DNA damage repair, metabolism and survival, as well as acts as an important subcellular target of resveratrol. The complex mechanisms underlying Sirt1 signaling during carcinogenesis remain controversial, as...

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Detalles Bibliográficos
Autores principales: Buhrmann, Constanze, Shayan, Parviz, Popper, Bastian, Goel, Ajay, Shakibaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808874/
https://www.ncbi.nlm.nih.gov/pubmed/26959057
http://dx.doi.org/10.3390/nu8030145

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