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Quercetin, Inflammation and Immunity

In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. Thi...

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Detalles Bibliográficos
Autores principales: Li, Yao, Yao, Jiaying, Han, Chunyan, Yang, Jiaxin, Chaudhry, Maria Tabassum, Wang, Shengnan, Liu, Hongnan, Yin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808895/
https://www.ncbi.nlm.nih.gov/pubmed/26999194
http://dx.doi.org/10.3390/nu8030167
Descripción
Sumario:In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. This review focuses on the physicochemical properties, dietary sources, absorption, bioavailability and metabolism of quercetin, especially main effects of quercetin on inflammation and immune function. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Nevertheless, further studies are needed to better characterize the mechanisms of action underlying the beneficial effects of quercetin on inflammation and immunity.