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Predicting the Cytotoxic Potency of Cigarette Smoke by Assessing the Thioredoxin Reductase Inhibitory Capacity of Cigarette Smoke Extract

The present study investigated the influence of the cigarette smoke extract (CSE) on mammalian thioredoxin reductase (TrxR) activity. TrxR is a selenoenzyme with a selenocysteine (Sec) residue exposed on the enzyme’s surface. This unique Sec residue is particularly susceptible to modification by num...

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Detalles Bibliográficos
Autores principales: Zhang, Longjie, Ning, Min, Xu, Yingbo, Wang, Chenghui, Zhao, Guangshan, Cao, Qingqing, Zhang, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809011/
https://www.ncbi.nlm.nih.gov/pubmed/27007390
http://dx.doi.org/10.3390/ijerph13030348

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