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Discovery of Novel Human Epidermal Growth Factor Receptor-2 Inhibitors by Structure-based Virtual Screening

BACKGROUND: Human epidermal growth factor receptor-2 (HER2) is a trans-membrane receptor like protein, and aberrant signaling of HER2 is implicated in many human cancers, such as ovarian cancer, gastric cancer, and prostate cancer, most notably breast cancer. Moreover, it has been in the spotlight i...

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Detalles Bibliográficos
Autores principales:	Shi, Zheng, Yu, Tian, Sun, Rong, Wang, Shan, Chen, Xiao-Qian, Cheng, Li-Jia, Liu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809169/ https://www.ncbi.nlm.nih.gov/pubmed/27076751 http://dx.doi.org/10.4103/0973-1296.177912

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