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Organometallic Palladium Reagents for Cysteine Bioconjugation
Transition-metal based reactions have found wide use in organic synthesis and are used frequently to functionalize small molecules.(1,2) However, there are very few reports of using transition-metal based reactions to modify complex biomolecules(3,4), which is due to the need for stringent reaction...
Autores principales: | Vinogradova, Ekaterina V., Zhang, Chi, Spokoyny, Alexander M., Pentelute, Bradley L., Buchwald, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809359/ https://www.ncbi.nlm.nih.gov/pubmed/26511579 http://dx.doi.org/10.1038/nature15739 |
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