Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

Beat-to-beat variability in repolarization (BVR) has been proposed as an arrhythmic risk marker for disease and pharmacological action. The mechanisms are unclear but BVR is thought to be a cell level manifestation of ion channel stochasticity, modulated by cell-to-cell differences in ionic conducta...

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Detalles Bibliográficos
Autores principales: Pueyo, E., Dangerfield, C. E., Britton, O. J., Virág, L., Kistamás, K., Szentandrássy, N., Jost, N., Varró, A., Nánási, P. P., Burrage, K., Rodríguez, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809506/
https://www.ncbi.nlm.nih.gov/pubmed/27019293
http://dx.doi.org/10.1371/journal.pone.0151461

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