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Crystal Structure of Human Myotubularin-Related Protein 1 Provides Insight into the Structural Basis of Substrate Specificity

Myotubularin-related protein 1 (MTMR1) is a phosphatase that belongs to the tyrosine/dual-specificity phosphatase superfamily. MTMR1 has been shown to use phosphatidylinositol 3-monophosphate (PI(3)P) and/or phosphatidylinositol 3,5-bisphosphate (PI(3,5)P(2)) as substrates. Here, we determined the c...

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Detalles Bibliográficos
Autores principales:	Bong, Seoung Min, Son, Kka-bi, Yang, Seung-Won, Park, Jae-Won, Cho, Jea-Won, Kim, Kyung-Tae, Kim, Hackyoung, Kim, Seung Jun, Kim, Young Jun, Lee, Byung Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809516/ https://www.ncbi.nlm.nih.gov/pubmed/27018598 http://dx.doi.org/10.1371/journal.pone.0152611

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