Cargando…

MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells

Chemotherapeutic insensitivity remains a major obstacle to treating osteosarcoma effectively. Recently, increasing evidence has suggested that microRNAs (miRNAs) are involved in drug resistance. However, the effect of miR-138 on cisplatin chemoresistance in osteosarcoma has not been reported. We use...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Ziqiang, Tang, Jinshan, Wang, Jianqiang, Duan, Gang, Zhou, Lei, Zhou, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809565/
https://www.ncbi.nlm.nih.gov/pubmed/27019355
http://dx.doi.org/10.1371/journal.pone.0150026