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TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways

The TRIB1 gene has been associated with multiple malignancies, plasma triglycerides and coronary artery disease (CAD). Despite the clinical significance of this pseudo-kinase, there is little information on the regulation of TRIB1. Previous studies reported TRIB1 mRNA to be unstable, hinting that TR...

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Detalles Bibliográficos
Autores principales: Soubeyrand, Sébastien, Martinuk, Amy, Lau, Paulina, McPherson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809572/
https://www.ncbi.nlm.nih.gov/pubmed/27019349
http://dx.doi.org/10.1371/journal.pone.0152346