Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire

High-throughput sequencing has recently been applied to profile the high diversity of antibodyome/B cell receptors (BCRs) and T cell receptors (TCRs) among immune cells. To date, Multiplex PCR (MPCR) and 5’RACE are predominately used to enrich rearranged BCRs and TCRs. Both approaches have advantage...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Zhang, Wei, Zeng, Xiaojing, Zhang, Ruifang, Du, Yuanping, Hong, Xueyu, Cao, Hongzhi, Su, Zheng, Wang, Changxi, Wu, Jinghua, Nie, Chao, Xu, Xun, Kristiansen, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809601/
https://www.ncbi.nlm.nih.gov/pubmed/27019362
http://dx.doi.org/10.1371/journal.pone.0152464

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