Cargando…

Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies

Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder characterized by the progressive loss of cholinergic neurons, leading to the onset of severe behavioral, motor and cognitive impairments. It is a pressing public health problem with no effective treatment. Existing therapies only...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onyango, Isaac G., Dennis, Jameel, Khan, Shaharyah M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809610/ https://www.ncbi.nlm.nih.gov/pubmed/27114851 http://dx.doi.org/10.14336/AD.2015.1007

Ejemplares similares

Modulation of mitochondrial bioenergetics as a therapeutic strategy in Alzheimer's disease
por: Onyango, Isaac G.
Publicado: (2018)

ATP Synthase and Mitochondrial Bioenergetics Dysfunction in Alzheimer’s Disease
por: Patro, Somya, et al.
Publicado: (2021)

Dysfunctional Mitochondrial Bioenergetics and Synaptic Degeneration in Alzheimer Disease
por: Tang, Jason, et al.
Publicado: (2019)

The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer’s Disease Pathology
por: Jové, Mariona, et al.
Publicado: (2021)

Mitochondrial Ca(2+) Signaling and Bioenergetics in Alzheimer’s Disease
por: Arnst, Nikita, et al.
Publicado: (2022)

Tackling Dysfunction of Mitochondrial Bioenergetics in the Brain
por: Zanfardino, Paola, et al.
Publicado: (2021)

Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases
por: Onyango, Isaac G., et al.
Publicado: (2021)

Bioenergetic failure, mitochondrial dysfunction and mitophagy
por: Beart, Philip
Publicado: (2015)

Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer's disease
por: Austad, Steven N., et al.
Publicado: (2022)

Bioenergetic Dysfunction and Inflammation in Alzheimer’s Disease: A Possible Connection
por: Wilkins, Heather M., et al.
Publicado: (2014)

The Rationale for Insulin Therapy in Alzheimer’s Disease
por: Ribarič, Samo
Publicado: (2016)

Dysfunctional mitochondrial bioenergetics and the pathogenesis of hepatic disorders
por: Auger, Christopher, et al.
Publicado: (2015)

Mitochondrially-Targeted Therapeutic Strategies for Alzheimer’s Disease
por: Onyango, Isaac G., et al.
Publicado: (2021)

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease
por: Joshi, Amit U., et al.
Publicado: (2017)

Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions
por: Protasoni, Margherita, et al.
Publicado: (2021)

Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease
por: Pérez, María J., et al.
Publicado: (2017)

Mitochondrial Dysfunction: Different Routes to Alzheimer's Disease Therapy
por: Picone, Pasquale, et al.
Publicado: (2014)

Link between the unfolded protein response and dysregulation of mitochondrial bioenergetics in Alzheimer’s disease
por: Poirier, Yannik, et al.
Publicado: (2019)

Mitochondrial Bioenergetics and Dynamism in the Failing Heart
por: Morciano, Giampaolo, et al.
Publicado: (2021)

Mitochondrial and bioenergetic dysfunction in trauma-induced painful peripheral neuropathy
por: Lim, Tony K. Y., et al.
Publicado: (2015)

Idiopathic Pulmonary Fibrosis: Aging, Mitochondrial Dysfunction, and Cellular Bioenergetics
por: Zank, Daniel C., et al.
Publicado: (2018)

Neuronal Mitochondrial Dysfunction and Bioenergetic Failure in Inflammation-Associated Depression
por: Casaril, Angela Maria, et al.
Publicado: (2021)

Deconstructing Mitochondrial Dysfunction in Alzheimer Disease
por: García-Escudero, Vega, et al.
Publicado: (2013)

Mitochondrial Dysfunction and Stress Responses in Alzheimer’s Disease
por: Weidling, Ian, et al.
Publicado: (2019)

Iron Dysregulation in Mitochondrial Dysfunction and Alzheimer’s Disease
por: Onukwufor, John O., et al.
Publicado: (2022)

Carnitines as Mitochondrial Modulators of Oocyte and Embryo Bioenergetics
por: Placidi, Martina, et al.
Publicado: (2022)

Impact of Hydrogen Sulfide on Mitochondrial and Bacterial Bioenergetics
por: Borisov, Vitaliy B., et al.
Publicado: (2021)

Bioenergetic Aspects of Mitochondrial Actions of Thyroid Hormones
por: Cioffi, Federica, et al.
Publicado: (2022)

Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
por: Gibellini, Lara, et al.
Publicado: (2020)

Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages
por: Neth, Bryan J., et al.
Publicado: (2017)

Rationale for the development of an Alzheimer’s disease vaccine
por: Kwan, Ping, et al.
Publicado: (2019)

Neuroinflammation in Alzheimer’s Disease
por: Onyango, Isaac G., et al.
Publicado: (2021)

Calcium Deregulation and Mitochondrial Bioenergetics in GDAP1-Related CMT Disease
por: González-Sánchez, Paloma, et al.
Publicado: (2019)

Cardiolipin, Non-Bilayer Structures and Mitochondrial Bioenergetics: Relevance to Cardiovascular Disease
por: Gasanoff, Edward S., et al.
Publicado: (2021)

Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease
por: Cabezas-Opazo, Fabian A., et al.
Publicado: (2015)

Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease
por: Ahmad, Faizan, et al.
Publicado: (2022)

Mitochondrial Dysfunctions in Neurodegenerative Diseases: Relevance to Alzheimer's Disease
por: Hroudová, Jana, et al.
Publicado: (2014)

Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future?
por: Bell, Simon M., et al.
Publicado: (2021)

The Translocator Protein (TSPO) in Mitochondrial Bioenergetics and Immune Processes
por: Betlazar, Calina, et al.
Publicado: (2020)

Mitochondrial Bioenergetics and Turnover during Chronic Muscle Disuse
por: Memme, Jonathan M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5eq3lj35npqeiqd18st2osoa58