Efficient Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models

Quantitative systems pharmacology models mechanistically describe a biological system and the effect of drug treatment on system behavior. Because these models rarely are identifiable from the available data, the uncertainty in physiological parameters may be sampled to create alternative parameteri...

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Detalles Bibliográficos
Autores principales: Allen, RJ, Rieger, TR, Musante, CJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809626/
https://www.ncbi.nlm.nih.gov/pubmed/27069777
http://dx.doi.org/10.1002/psp4.12063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809626/
https://www.ncbi.nlm.nih.gov/pubmed/27069777
http://dx.doi.org/10.1002/psp4.12063

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