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Efficient Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models
Quantitative systems pharmacology models mechanistically describe a biological system and the effect of drug treatment on system behavior. Because these models rarely are identifiable from the available data, the uncertainty in physiological parameters may be sampled to create alternative parameteri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809626/ https://www.ncbi.nlm.nih.gov/pubmed/27069777 http://dx.doi.org/10.1002/psp4.12063 |