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miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway
Acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib, is a critical issue for the treatment of EGFR mutant-positive non-small cell lung cancer (NSCLC). Recent evidence supports the role of microRNA-223 (miR-223) in modulati...
Autores principales: | HAN, JING, ZHAO, FENGYI, ZHANG, JING, ZHU, HAIZHEN, MA, HU, LI, XUETAO, PENG, LINA, SUN, JIANGUO, CHEN, ZHENGTANG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809653/ https://www.ncbi.nlm.nih.gov/pubmed/26936292 http://dx.doi.org/10.3892/ijo.2016.3401 |
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