EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis in Human Myeloid Leukemia Cells through Thioredoxin- and Reactive Oxygen Species-Mediated Signaling Pathways

Elephantopus mollis (EM) is a traditional herbal medicine with multiple pharmacological activities. However, the efficacy of EM in treating human leukemia is currently unknown. In the current study, we report that EM23, a natural sesquiterpene lactone isolated from EM, inhibits the proliferation of...

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Detalles Bibliográficos
Autores principales: Li, Hongyu, Li, Manmei, Wang, Guocai, Shao, Fangyuan, Chen, Wenbo, Xia, Chao, Wang, Sheng, Li, Yaolan, Zhou, Guangxiong, Liu, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809879/
https://www.ncbi.nlm.nih.gov/pubmed/27064563
http://dx.doi.org/10.3389/fphar.2016.00077

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