Cargando…

Integrating Immunologic Signaling Networks: The JAK/STAT Pathway in Colitis and Colitis-Associated Cancer

Cytokines are believed to be crucial mediators of chronic intestinal inflammation in inflammatory bowel diseases (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC). Many of these cytokines trigger cellular effects and functions through signaling via janus kinase (JAK) and signal transduc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zundler, Sebastian, Neurath, Markus F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810057/ https://www.ncbi.nlm.nih.gov/pubmed/26938566 http://dx.doi.org/10.3390/vaccines4010005

Ejemplares similares

Mechanisms of Immune Signaling in Colitis-Associated Cancer
por: Waldner, Maximilian J., et al.
Publicado: (2014)

Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis
por: Lindemann, Aylin, et al.
Publicado: (2023)

Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles
por: Fuchs, Friederike, et al.
Publicado: (2017)

Differential regulation of JAK/STAT-signaling in patients with ulcerative colitis and Crohn’s disease
por: Cordes, Friederike, et al.
Publicado: (2020)

Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice
por: Heichler, Christina, et al.
Publicado: (2022)

Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway
por: Wang, Liang, et al.
Publicado: (2021)

TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway
por: Wang, Jiajia, et al.
Publicado: (2020)

Huanglian Jiedu Decoction ameliorates DSS-induced colitis in mice via the JAK2/STAT3 signalling pathway
por: Lu, Zhuo, et al.
Publicado: (2020)

Case Report: IBD-like colitis following CAR T cell therapy for diffuse large B cell lymphoma
por: Zundler, Sebastian, et al.
Publicado: (2023)

JAK-STAT and intestinal mucosal immunology
por: Heneghan, Aaron F, et al.
Publicado: (2013)

Calcineurin B in CD4(+) T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway
por: Mencarelli, Andrea, et al.
Publicado: (2018)

Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis
por: Zhao, Hai-Mei, et al.
Publicado: (2016)

Krüppel-Like Factor 5 Protects against Murine Colitis and Activates JAK-STAT Signaling In Vivo
por: Tetreault, Marie-Pier, et al.
Publicado: (2012)

Healing of the epithelial barrier in the ileum is superior to endoscopic and histologic remission for predicting major adverse outcomes in ulcerative colitis
por: Rath, Timo, et al.
Publicado: (2023)

JAK-STAT Signalling Pathway in Cancer
por: Brooks, Andrew J., et al.
Publicado: (2020)

Endomicroscopic Imaging of COX-2 Activity in Murine Sporadic and Colitis-Associated Colorectal Cancer
por: Foersch, Sebastian, et al.
Publicado: (2013)

Vedolizumab blocks α4β7 integrin-mediated T cell adhesion to MAdCAM-1 in microscopic colitis
por: Besendorf, Laura, et al.
Publicado: (2022)

Efficacy of JAK inhibitors in Ulcerative Colitis
por: Ferrante, Marc, et al.
Publicado: (2020)

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
por: Waldner, Maximilian J., et al.
Publicado: (2010)

Butyric Acid Increases the Therapeutic Effect of EHLJ7 on Ulcerative Colitis by Inhibiting JAK2/STAT3/SOCS1 Signaling Pathway
por: Tang, Xiaonan, et al.
Publicado: (2020)

Helicobacter hepaticus Induce Colitis in Male IL-10(−/−) Mice Dependent by Cytolethal Distending Toxin B and via the Activation of Jak/Stat Signaling Pathway
por: Zhu, Liqi, et al.
Publicado: (2021)

YAP Activates STAT3 Signalling to Promote Colonic Epithelial Cell Proliferation in DSS-Induced Colitis and Colitis Associated Cancer
por: Deng, Feihong, et al.
Publicado: (2022)

Immunology of IL-12: An update on functional activities and implications for disease
por: Ullrich, Karen A.-M., et al.
Publicado: (2020)

Mechanism of Sishen-Pill-Regulated Special Memory T and mTfh Cell via Involving JAK/STAT5 Pathway in Colitis Mice
por: Wang, Mengxue, et al.
Publicado: (2022)

Chemopreventive Effects of Silibinin on Colitis-Associated Tumorigenesis by Inhibiting IL-6/STAT3 Signaling Pathway
por: Zheng, Rongjuan, et al.
Publicado: (2018)

JAK Inhibitors Safety in Ulcerative Colitis: Practical Implications
por: Agrawal, Manasi, et al.
Publicado: (2020)

Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis
por: Voskens, Caroline, et al.
Publicado: (2023)

The Jak/Stat Signaling Pathway Is Downregulated at Febrile Temperatures
por: Nespital, Tobias, et al.
Publicado: (2012)

Myeloproliferative neoplasms and the JAK/STAT signaling pathway: an overview
por: de Freitas, Renata Mendes, et al.
Publicado: (2015)

The JAK/STAT signaling pathway: from bench to clinic
por: Hu, Xiaoyi, et al.
Publicado: (2021)

Is the JAK-STAT Signaling Pathway Involved in the Pathogenesis of Depression?
por: Gałecka, Małgorzata, et al.
Publicado: (2022)

HBD Inhibits the Development of Colitis-Associated Cancer in Mice via the IL-6R/STAT3 Signaling Pathway
por: Deng, Song, et al.
Publicado: (2019)

JAK‐STAT core cancer pathway: An integrative cancer interactome analysis
por: Erdogan, Fettah, et al.
Publicado: (2022)

Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer
por: Tang, Shengbo, et al.
Publicado: (2019)

Increased Motility and Suppression of Ex Vivo–Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis
por: Müller, Tanja M., et al.
Publicado: (2023)

Baseline levels of dynamic CD4(+) T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study
por: Allner, Clarissa, et al.
Publicado: (2020)

The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

The JAK-STAT pathway at 20
por: Darnell, Jr., James E.
Publicado: (2012)

Integrating non-coding RNAs in JAK-STAT regulatory networks
por: Witte, Steven, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4p0hu35nfrsu5ads6mgmurai20