Cargando…

Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

The development of subunit vaccines has become very attractive in recent years due to their superior safety profiles as compared to traditional vaccines based on live attenuated or whole inactivated pathogens, and there is an unmet medical need for improved vaccines and vaccines against pathogens fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tandrup Schmidt, Signe, Foged, Camilla, Smith Korsholm, Karen, Rades, Thomas, Christensen, Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810083/ https://www.ncbi.nlm.nih.gov/pubmed/26978390 http://dx.doi.org/10.3390/pharmaceutics8010007

Ejemplares similares

Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
por: Schmidt, Signe Tandrup, et al.
Publicado: (2018)

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
por: Schmidt, Signe Tandrup, et al.
Publicado: (2016)

Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction
por: Wørzner, Katharina, et al.
Publicado: (2021)

Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b
por: Schmidt, Signe Tandrup, et al.
Publicado: (2020)

A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease
por: Zimmermann, Julie, et al.
Publicado: (2022)

Nanoparticulate Tubular Immunostimulating Complexes: Novel Formulation of Effective Adjuvants and Antigen Delivery Systems
por: Sanina, Nina, et al.
Publicado: (2017)

Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo
por: Huber, Alexandra, et al.
Publicado: (2016)

Food-Grade Saponin Extract as an Emulsifier and Immunostimulant in Emulsion-Based Subunit Vaccine for Pigs
por: Burakova, Yulia, et al.
Publicado: (2018)

Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators
por: Barnier-Quer, Christophe, et al.
Publicado: (2013)

Intranasal Delivery of Influenza Subunit Vaccine Formulated with GEM Particles as an Adjuvant
por: Saluja, Vinay, et al.
Publicado: (2010)

The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics
por: Webb, Cameron, et al.
Publicado: (2019)

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis
por: Mustafa, Abu Salim
Publicado: (2021)

A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21
por: Techawiwattanaboon, Teerasit, et al.
Publicado: (2020)

Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA
por: Kabilova, Tatyana, et al.
Publicado: (2018)

Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone
por: Thakur, Aneesh, et al.
Publicado: (2020)

Combinational PRR Agonists in Liposomal Adjuvant Enhances Immunogenicity and Protective Efficacy in a Tuberculosis Subunit Vaccine
por: Hao, Ling, et al.
Publicado: (2020)

Carbohydrate Immune Adjuvants in Subunit Vaccines
por: Bashiri, Sahra, et al.
Publicado: (2020)

The Potency of an Anti-MERS Coronavirus Subunit Vaccine Depends on a Unique Combinatorial Adjuvant Formulation
por: George, Parakkal Jovvian, et al.
Publicado: (2020)

Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System
por: Badhan, Raj K. S., et al.
Publicado: (2017)

Studies on the Use of Flagellin as an Immunostimulant and Vaccine Adjuvant in Fish Aquaculture
por: Wangkahart, Eakapol, et al.
Publicado: (2019)

Micelle-Based Adjuvants for Subunit Vaccine Delivery
por: Trimaille, Thomas, et al.
Publicado: (2015)

Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster
por: Mao, Lirong, et al.
Publicado: (2022)

Injection Vaccines Formulated with Nucleotide, Liposomal or Mineral Oil Adjuvants Induce Distinct Differences in Immunogenicity in Rainbow Trout
por: Rømer Villumsen, Kasper, et al.
Publicado: (2020)

Modulation of Immunogenicity and Conformation of HA1 Subunit of Influenza A Virus H1/N1 Hemagglutinin in Tubular Immunostimulating Complexes
por: Sanina, Nina, et al.
Publicado: (2017)

Duality of β-glucan microparticles: antigen carrier and immunostimulants
por: Baert, Kim, et al.
Publicado: (2016)

Designing Adjuvant Formulations to Promote Immunogenicity and Protective Efficacy of Leptospira Immunoglobulin-Like Protein A Subunit Vaccine
por: Techawiwattanaboon, Teerasit, et al.
Publicado: (2022)

Adjuvant Selection for Influenza and RSV Prefusion Subunit Vaccines
por: Isaacs, Ariel, et al.
Publicado: (2021)

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization
por: Thakur, Aneesh, et al.
Publicado: (2018)

Evaluation of a Unani polyherbal formulation (Tiryaqe wabai) as an immunostimulator in elderly persons
por: Nigar, Zar, et al.
Publicado: (2013)

Licensed liposomal vaccines and adjuvants in the antigen delivery system
por: Krasnopolsky, Yuriy, et al.
Publicado: (2022)

Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants
por: Martelet, Léa, et al.
Publicado: (2017)

Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection
por: Kwon, Kee Woong, et al.
Publicado: (2023)

Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis
por: Ravindran, Rajesh, et al.
Publicado: (2010)

Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements
por: Agger, Else Marie, et al.
Publicado: (2008)

Sub-Chronic Safety Evaluation of Ayurvedic Immunostimulant Formulation ‘Immuforte’ in Rats in Reverse Pharmacology
por: Dhumal, Rohit, et al.
Publicado: (2013)

Effect of Aluminum Adjuvant and Preservatives on Structural Integrity and Physicochemical Stability Profiles of Three Recombinant Subunit Rotavirus Vaccine Antigens
por: Agarwal, Sanjeev, et al.
Publicado: (2020)

Evaluation of glycoprotein E subunit and live attenuated varicella‐zoster virus vaccines formulated with a single‐strand RNA‐based adjuvant
por: Lee, Su Jeen, et al.
Publicado: (2020)

Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice
por: Wørzner, Katharina, et al.
Publicado: (2021)

Xanthan Gum as an Adjuvant in a Subunit Vaccine Preparation against Leptospirosis
por: Bacelo, Katia L., et al.
Publicado: (2014)

Adjuvants Differentially Modulate the Immunogenicity of Lassa Virus Glycoprotein Subunits in Mice
por: To, Albert, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4tdf3u7jtrq3ijgjng93vcr6t4