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Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy

This review is focused on different subsets of T cells: CD4 and CD8, memory and effector functions, and their role in CAR-T therapy––a cellular adoptive immunotherapy with T cells expressing chimeric antigen receptor. The CAR-T cells recognize tumor antigens and induce cytotoxic activities against t...

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Detalles Bibliográficos
Autores principales: Golubovskaya, Vita, Wu, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810120/
https://www.ncbi.nlm.nih.gov/pubmed/26999211
http://dx.doi.org/10.3390/cancers8030036