Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of Na(V)1.7-Mediated Pain

Loss-of-function mutations of Na(V)1.7 lead to congenital insensitivity to pain, a rare condition resulting in individuals who are otherwise normal except for the inability to sense pain, making pharmacological inhibition of Na(V)1.7 a promising therapeutic strategy for the treatment of pain. We cha...

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Detalles Bibliográficos
Autores principales: Deuis, Jennifer R., Wingerd, Joshua S., Winter, Zoltan, Durek, Thomas, Dekan, Zoltan, Sousa, Silmara R., Zimmermann, Katharina, Hoffmann, Tali, Weidner, Christian, Nassar, Mohammed A., Alewood, Paul F., Lewis, Richard J., Vetter, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810223/
https://www.ncbi.nlm.nih.gov/pubmed/26999206
http://dx.doi.org/10.3390/toxins8030078

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