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The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice
Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse set of viruses. A novel iminosugar, UV-4B, has recently been shown to provide protection against lethal infections with dengue and influenza A...
Autores principales: | Warfield, Kelly L., Barnard, Dale L., Enterlein, Sven G., Smee, Donald F., Khaliq, Mansoora, Sampath, Aruna, Callahan, Michael V., Ramstedt, Urban, Day, Craig W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810261/ https://www.ncbi.nlm.nih.gov/pubmed/27072420 http://dx.doi.org/10.3390/v8030071 |
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