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CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses

The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications. Therefore, a new generation of more potent oncolyt...

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Detalles Bibliográficos
Autores principales: Yuan, Ming, Webb, Eika, Lemoine, Nicholas Robert, Wang, Yaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810262/
https://www.ncbi.nlm.nih.gov/pubmed/26959050
http://dx.doi.org/10.3390/v8030072