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G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are assembled into discrete granules by specific RNA-binding proteins such as G3BP. We now show that cells lacking both G3BP1 and G3BP2 cannot form SGs in response to eukaryotic initiation factor 2α phosphorylat...
Autores principales: | Kedersha, Nancy, Panas, Marc D., Achorn, Christopher A., Lyons, Shawn, Tisdale, Sarah, Hickman, Tyler, Thomas, Marshall, Lieberman, Judy, McInerney, Gerald M., Ivanov, Pavel, Anderson, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810302/ https://www.ncbi.nlm.nih.gov/pubmed/27022092 http://dx.doi.org/10.1083/jcb.201508028 |
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