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Amplification of actin polymerization forces

The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple configurations where the force developed by the network can exceed the sum of t...

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Detalles Bibliográficos
Autores principales: Dmitrieff, Serge, Nédélec, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810308/
https://www.ncbi.nlm.nih.gov/pubmed/27002174
http://dx.doi.org/10.1083/jcb.201512019
Descripción
Sumario:The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple configurations where the force developed by the network can exceed the sum of the polymerization forces from all filaments.